Isha is a graduate in Life Sciences from Ruia College in Mumbai. Her modelling career started when she was studying in junior college and did a photo shoot with Gautam Rajyadhaksa. After that she got many ad assignments with leading brands like Camay, Rexona, L'Oreal, Tips & Toes, Coke, Synergy, Ponds, Deepam Sarees, and also walked the ramp many times.
Isha entered bollywood with doing cameos in the movies. But she got her much awaited recognition and fame from the item number (Khallas) in Ram Gopal Verma’s "Company", and from then she has being called the “Khallas Girl”. And now she has become a household name and has many good movies lined up for release in the coming months like Ek Vivaah Aisa Bhi, Money Hai Toh Honey Hai and Right Ya Wrong.
Apart from acting Isha, performs at many music stage shows. Also, she has appeared in two music videos: Patli Kamar by KK for a private album by Sony and Bandish Projekt's Bhor (Satyam Shivam Sundaram) in 2004, choreographed by Bosco-Caesar. In 2006 she even performed onstage in the Indian Idol Grand Final with the two finalists, and 2007 she was one of the three judges in the celebrity dance competition Nach Baliye 3, alongside director David Dhawan and Vaibhavi Merchant.